Or what if Earth never developed Warp . . . but a different form of travel, Say a form of the B5 Hyperspace . . . developing their own transwarp wormholes or such.
Or what if after a nuclear war started by an Iran/Russian/United States Conflict . . . lead to a birth of Jedism as the prevailing worldwide religion . . . thanks to a small group of Jedist in Perth being the predominate techonologically advanced surviving group.
Or what if the Bajorans went all militant with their early advanced technology and decided to lord over their area of space, and start expanding thereafter.
Or what if the Andorians had found a way of subjecting the Vulcans early on, prior to anyone getting involved with Earth . . . and a neighboring species decided to "enlighten" us, and bring us up to help them against the torenting Andorians?
Or what if the Voth had never left the System . . . and returned to Earth . . . and brought up evolving primates to be a subjegated species?
Or what if all those conspiricy theories with the Grey's and the Illuminate are true . . . and they are really in cohoots with each other . . . and are purposfully keeping Earth primative, yet protecting the system from external influences.
Or what if all the cetaceans were secretly an advanced technologically and right before the planet was cleared for demolition . . . and just as the first sleeper colony ship was about to launch . . . launched their own sleeper ship of their own . . . causing the human sleeper ship to halt . . . and then get demolited with the planet.