With what happened with the Xindi, I assume they do like the romulans and retreat behind their borders reassessing what they want to do in the galaxy at large. I"m sure you could have factions within starfleet trying to open relations with them and I'm sure they would agree to dialogue. But because they are so fractured within as a society especially after killing so may humans, I think they will take their time decisding their future. But I'm also sure there could be some Reptile/Insectoid XIndi's that might continue skimishes with starfleet ships.