Likely the Milky Way will swallow up the LMC and GMC like it's eating the Sagittarius and Leo dwarf galaxies.
Andromeda (M-31) is also plunging towards the Milky way. It should get here in about 4-5 billion years... round about the time that the Sun burns out.
Given that Andromeda is almost twice our galaxy's size, it may eat us. At the very least it will provide some interesting gravitational interactions to any outside observers.
"It's hard being an evil genius when everybody else is so stupid" -- Quantum Crook