I think I figured it out.
As I understand it a replicator combines base elements from a storage tank(s) and combines them in a specific order and pattern (ie. form ans substance).
What if items like latinum require a base element rare enough that to find it in nature you have to have phenomenal luck.
As such the material in question can still be transported, just not replicated.
What do you think?
Red
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"Being afraid all of the time of forgetting somebody's name. Not...not knowing what to do with your hands...I mean, I am the guy who writes down things to remember to say when there's a party. And then when he finally gets there, he winds up alone in the corner trying to look comfortable examining a potted plant."
-Lieutentant Reginald Barclay